Primary Hypertension — USMLE Step 2 CK MCQ
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Correct answer: B — Begin one first-line antihypertensive medication and continue lifestyle therapy
B is correct: current US guidance recommends medication plus lifestyle therapy for stage 1 hypertension when 10-year PREVENT cardiovascular risk is at least 7.5%. A uses the wrong threshold. C is preferred for stage 2 hypertension, not this modest elevation. D does not use a first-line class without another indication. E neither treats hypertension nor appropriately substitutes for antihypertensive therapy.
Reference: 2025 AHA/ACC high blood pressure guideline: top things to know. https://professional.heart.org/en/science-news/2025-high-blood-pressure-guideline/top-things-to-know