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Pelvic Inflammatory Disease — USMLE Step 2 CK MCQ

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ModerateInfectious DiseasesPelvic Inflammatory DiseaseUSMLE Step 2 CK

A 23-year-old with pelvic pain and cervical motion tenderness is diagnosed with PID. She is nonpregnant and can tolerate oral meds. Which outpatient regimen is preferred?

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Correct answer: C — Ceftriaxone 500 mg IM ×1 + doxycycline 100 mg BID ×14 days + metronidazole 500 mg BID ×14 days

CDC recommends ceftriaxone 500 mg IM once plus doxycycline and metronidazole for 14 days for outpatient PID. A uses outdated ceftriaxone dosing/duration. B is an inpatient IV approach. D and E lack adequate coverage for likely pathogens, including anaerobes and gonorrhea.

Reference: CDC (2021): STI Treatment Guidelines-Pelvic Inflammatory Disease