Maternal RSV Immunization — USMLE Step 2 CK MCQ

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MediumObstetrics & GynecologyMaternal RSV ImmunizationUSMLE Step 2 CK

In RSV season, a 33-week pregnant patient at 34 weeks asks about maternal RSV vaccination. Best recommendation?

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Correct answer: B — Administer maternal RSVpreF vaccine at 32-36 weeks' gestation (seasonal)

ACIP recommends a single dose of RSVpreF vaccine during 32-36 weeks' gestation during RSV season to protect infants via passive immunity. Palivizumab is for certain high-risk infants; 20 weeks and delivery are incorrect windows; nirsevimab is an alternative infant-focused strategy.

Reference: https://www.cdc.gov/#stage-9-order-59