Rabies Exposure — USMLE Step 2 CK MCQ
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Correct answer: B — Rabies immune globulin 20 IU/kg infiltrated into wound plus vaccine days 0, 3, 7, and 14
For previously unvaccinated persons, infiltrate HRIG 20 IU/kg into and around wound with remainder IM at a distant site, plus vaccine on days 0, 3, 7, and 14. A/C: Schedules incomplete/incorrect for immunocompetent. E: Not appropriate for high-risk exposure. D: Not appropriate for high-risk exposure.
Reference: ACIP Recommendation (2022): Rabies Post-Exposure Prophylaxis