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Pulmonary Embolism — UKMLA MCQ

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HardRespiratory MedicinePulmonary EmbolismUKMLAMRCEM SBAMRCP Part 1PARA

In August 2026, a White British adult has BMI 36 kg/m² plus hypertension, dyslipidaemia, obstructive sleep apnoea and cardiovascular disease despite sustained diet and activity support. Type 2 diabetes is absent. Which statement reflects the current phased NHS implementation of NICE guidance for tirzepatide used for weight management?

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Correct answer: A — Offer tirzepatide with reduced-calorie diet and increased physical activity

The best answer is “Offer tirzepatide with reduced-calorie diet and increased physical activity”. The core NICE recommendation requires BMI of at least 35 kg/m² plus at least one weight-related comorbidity, alongside reduced-calorie diet and increased activity. Phased implementation expanded from around June 2026 to people with BMI 35.0 to 39.9 kg/m² who have at least four listed conditions. This patient has exactly four: hypertension, dyslipidaemia, sleep apnoea and cardiovascular disease. Diabetes and previous bariatric surgery are not additional requirements.

Reference: NICE TA1026, Tirzepatide for managing overweight and obesity: https://www.nice.org.uk/guidance/ta1026/chapter/1-Recommendations