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Severe Acne — UKMLA MCQ

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HardDermatologySevere AcneUKMLAMRCGP AKTPARAPSA

A 17-year-old being considered for isotretinoin has severe scarring acne and a history of depression that is currently stable. Which statement best reflects current UK safety practice?

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Correct answer: A — Assess mental and sexual health

The best answer is “Assess mental and sexual health”. Current UK safety measures require specialist oversight and explicit assessment and monitoring of mental-health and sexual-function concerns alongside stringent pregnancy-prevention requirements where relevant. A past mental-health condition is not an automatic permanent contraindication, but it changes counselling and monitoring. Safety review continues during treatment rather than ending after initiation.

Reference: MHRA: Isotretinoin safety measures: https://www.gov.uk/drug-safety-update/isotretinoin-roaccutanev-new-safety-measures-to-be-introduced-in-the-coming-months-including-additional-oversight-on-initiation-of-treatment-for-patients-under-18-years