For primary prevention, baseline total cholesterol is 6.5 mmol/L and HDL cholesterol 1.3 mmol/L. After atorvastatin 20 mg, total cholesterol is 4.8

Question

For primary prevention, baseline total cholesterol is 6.5 mmol/L and HDL cholesterol 1.3 mmol/L. After atorvastatin 20 mg, total cholesterol is 4.8 mmol/L and HDL cholesterol 1.2 mmol/L. Adherence is confirmed and treatment is tolerated. Which interpretation is correct?

Accepted Answer

The non-HDL reduction is about 31%, so consider dose intensification

Answer

Non-HDL cholesterol has fallen by over 50%, so reduce the statin

Answer

LDL cholesterol alone proves the primary-prevention target is achieved

Answer

Any fall is adequate, so no treatment review is required

Answer

HDL has fallen slightly, so stop all lipid-lowering treatment

Lipid Management — UKMLA MCQ

For primary prevention, baseline total cholesterol is 6.5 mmol/L and HDL cholesterol 1.3 mmol/L. After atorvastatin 20 mg, total cholesterol is 4.8 mmol/L and HDL cholesterol 1.2 mmol/L. Adherence is confirmed and treatment is tolerated. Which interpretation is correct?