A 55-year-old woman with rheumatoid arthritis, treated with methotrexate 15mg once weekly and folic acid 5mg once weekly, presents for routine monitor...

Question

A 55-year-old woman with rheumatoid arthritis, treated with methotrexate 15mg once weekly and folic acid 5mg once weekly, presents for routine monitoring blood tests. Which test result would necessitate immediate cessation of methotrexate?

Accepted Answer

White cell count 2.5 x10^9/L (Normal 4-11)

Answer

Haemoglobin 105 g/L

Answer

ALT 80 U/L (Normal

Answer

Platelets 130 x10^9/L (Normal 150-400)

Answer

Creatinine 110 umol/L (Normal 60-100)

ukmla MCQ (SBA): Methotrexate Monitoring

A 55-year-old woman with rheumatoid arthritis, treated with methotrexate 15mg once weekly and folic acid 5mg once weekly, presents for routine monitoring blood tests. Which test result would necessitate immediate cessation of methotrexate?