skip to main content

Variceal bleeding — UKMLA MCQ

Instant feedback + full explanation. One question, done properly.

MediumGastroenterologyVariceal bleedingUKMLAMRCP Part 1

A 65-year-old with chronic liver disease presents with haematemesis. Endoscopy confirms variceal bleeding. Which pharmacological agent should be given first to reduce portal pressure?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Octreotide (somatostatin analogue)

In acute variceal bleeding, vasoactive agents such as octreotide (or terlipressin) should be started immediately to reduce portal blood flow. IV omeprazole is used for peptic ulcers, not specifically for varices. Beta-blockers are for prophylaxis, not acute management.

Reference: NICE Acute Upper GI Bleeding Guideline