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Hodgkin lymphoma — UKMLA MCQ

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HardHaematologyHodgkin lymphomaUKMLAMRCP Part 1

A 72-year-old with community-acquired pneumonia is orientated, has urea 6.5 mmol/L, respiratory rate 24/min and blood pressure 128/72 mmHg. CURB65 is therefore 1, but oxygen saturation is 82% on air and lactate is 4.1 mmol/L. What is the best disposition?

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Correct answer: BArrange urgent hospital treatment and senior assessment for possible organ support

The best answer is “Arrange urgent hospital treatment and senior assessment for possible organ support”. CURB65 supports but does not replace clinical judgement or direct physiological assessment. Profound hypoxaemia and hyperlactataemia indicate severe compromise and possible tissue hypoperfusion even though the five-variable score is only 1. This patient needs urgent hospital treatment, prompt senior review, controlled oxygen, antibiotics and assessment for respiratory or circulatory support. Repeating lactate and applying another score can refine response and prognosis, but neither should delay escalation. A low CURB65 value cannot make markedly abnormal gas exchange suitable for ambulatory care.

Reference: NICE NG250: Pneumonia diagnosis and management: https://www.nice.org.uk/guidance/ng250/chapter/Recommendations