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Depression — PSA MCQ

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EasyMental Health & PsychiatryDepressionPSA

A 28-year-old woman with moderate depression and no significant other medical history is being considered for antidepressant therapy. According to BNF guidance, which class of antidepressant is usually considered first-line?

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Correct answer: A — Selective serotonin reuptake inhibitors (SSRIs)

SSRIs are typically recommended as first-line pharmacological treatment for moderate to severe depression in adults due to their relatively favourable side-effect profile and safety in overdose. Tricyclic antidepressants and MAOIs have more side effects and are usually not first-line. SNRIs are an alternative if SSRIs are not suitable or tolerated.

Reference: BNF Antidepressants