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Non-alcoholic fatty liver disease — UKMLA MCQ

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EasyGastroenterologyNon-alcoholic fatty liver diseaseUKMLA

A 50-year-old man presents with suspected non-alcoholic fatty liver disease (NAFLD). He has a BMI of 33 kg/m². According to NICE, which of the following interventions is a key part of the initial management strategy?

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Correct answer: C — Lifestyle modifications including weight reduction

Lifestyle modifications, particularly weight reduction through diet and exercise, are recommended as the cornerstone of NAFLD management by NICE. Pharmacotherapy (e.g., vitamin E or pioglitazone) may be considered in select cases, but not before lifestyle interventions. Steroids and ursodeoxycholic acid are not standard therapies for NAFLD. ERCP is unrelated to NAFLD management.

Reference: NICE Non-Alcoholic Fatty Liver Disease Guideline