Urinary Tract Infection — MRCGP AKT MCQ

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EasyRenal medicine & UrologyUrinary Tract InfectionMRCGP AKT

A 30-year-old woman with recurrent UTIs. According to NICE CKS, which antibiotic is recommended first-line empirically for uncomplicated lower UTI in non-pregnant women?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Trimethoprim or Nitrofurantoin

Nitrofurantoin or trimethoprim are recommended first-line if there are no contraindications, with local resistance patterns considered. [1] The keyed option is the best answer only in the stated clinical context. The alternatives would require different findings, contraindications, thresholds or treatment circumstances that are not present. Apply the recommendation alongside comorbidity, interactions, patient preference and the current local pathway. Review response and safety-net for deterioration, treatment failure or adverse effects; reconsider the diagnosis if the expected response does not occur.

Reference: NICE CKS Urinary Tract Infection: https://www.nice.org.uk/guidance/ng109/chapter/recommendations