Zollinger-Ellison Syndrome
Overview and management.
Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
Clinical Guidelines
American Association of Clinical Endocrinology Consensus Statement: Management of Multiple Endocrine Neoplasia Type 1 and Zollinger-Ellison Syndrome
National
ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Tumors: Well-Differentiated Gastric, Duodenal, and Rectal Neuroendocrine TumorsNational
Neuroendocrine gastro-entero-pancreatic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-upNational
American Association of Clinical Endocrinology Consensus Statement: Management of Multiple Endocrine Neoplasia Type 1 and Associated Zollinger-Ellison SyndromeLocal
ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Tumors: Well-Differentiated Gastric Neuroendocrine Neoplasms and Zollinger-Ellison SyndromeLocal
European Neuroendocrine Tumor Society 2023 guidance paper for the diagnosis and management of gastrinoma (Zollinger-Ellison syndrome)Local
JNETS clinical practice guidelines for gastroenteropancreatic neuroendocrine neoplasmsLocal
NANETS Consensus Guidelines: Management of the Zollinger-Ellison syndrome in patients with multiple endocrine neoplasia type 1Local
The North American Neuroendocrine Tumor Society Consensus Guidelines: Surveillance and Medical Management of Pancreatic Neuroendocrine TumorsLocal