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Knowledge Centre / Sciatica

Sciatica

Management of nerve root pain in the leg.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
MusculoskeletalNeurology

Clinical Guidelines

CKS: Sciatica (lumbar radiculopathy)
National
NICE guideline [NG59]
National
NICE guideline [NG59]: Low back pain and sciatica in over 16s: assessment and management
National
SIGN 136 • Management of chronic pain
National
ACP Clinical Practice Guideline: Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain
Local
Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care: Diagnosis and Treatment of Low Back Pain
Local
NICE guideline [NG59]: Low back pain and sciatica in over 16s: assessment and management
Local
VA/DoD Clinical Practice Guideline: Diagnosis and Treatment of Low Back Pain
Local

Recent iatroX Q&As

  • What are the recommended first-line treatments for a patient presenting with acute sciatica symptoms?Updated: 8/16/2025
  • How can I differentiate between sciatica caused by a herniated disc and other potential causes of nerve root pain?Updated: 8/16/2025
  • What criteria should I use to determine if a patient with sciatica requires referral for surgical evaluation?Updated: 8/16/2025
  • What role do imaging studies play in the management of sciatica in primary care settings?Updated: 8/16/2025
  • How should I approach the management of chronic sciatica in a patient who has not responded to conservative treatment?Updated: 8/16/2025
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