Peptic Ulcer Disease

Management of gastric and duodenal ulcers.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MSt MRCGP (General Practitioner)

Last reviewed: 21 October 2025

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Clinical Guidelines

BNF: Peptic ulcer disease

CKS: Dyspepsia - proven peptic ulcer

NICE guideline CG184: Dyspepsia and gastro-oesophageal reflux disease

SIGN guideline: Upper Gastrointestinal Bleeding

ACG Clinical Guideline: Treatment of Helicobacter pylori Infection

Consensus conference. Medical treatment of peptic ulcer disease. Practice guidelines. Practice Parameters Committee of the American College of Gastroenterology

Evidence-based clinical practice guidelines for peptic ulcer disease 2020 (Japanese Society of Gastroenterology)

Practice Guidelines for Treatment of Peptic Ulcer Disease (JAMA)

WSES Guidelines: Perforated and bleeding peptic ulcer