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Knowledge Centre / Fatigue (Chronic)

Fatigue (Chronic)

Assessment of persistent tiredness.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
General Practice

Clinical Guidelines

NICE guideline [NG206]: Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management
National
Canadian Consensus Document: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Clinical Case Definition and Guidelines for Medical Practitioners
Local
Clinical Practice Guidelines | Sjögren's Foundation
Local
Korean Medicine Clinical Practice Guideline for Chronic Fatigue
Local
NICE guideline 2021: Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management
Local

Recent iatroX Q&As

  • What initial assessments should I perform for a patient presenting with chronic fatigue to rule out underlying medical conditions?Updated: 8/22/2025
  • Which red flag symptoms in a patient with chronic fatigue should prompt immediate referral to secondary care?Updated: 8/22/2025
  • What are the recommended lifestyle modifications and management strategies for patients diagnosed with chronic fatigue syndrome?Updated: 8/22/2025
  • How can I effectively use screening tools to evaluate the severity and impact of chronic fatigue on a patient's daily life?Updated: 8/22/2025
  • What follow-up protocols should I implement for patients with chronic fatigue to monitor their progress and response to treatment?Updated: 8/22/2025
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