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Knowledge Centre / Drug Allergy and Hypersensitivity

Drug Allergy and Hypersensitivity

Assessment and management of allergic reactions to medications.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
AllergyPharmacologyImmunology

Clinical Guidelines

CKS: Angio-oedema and anaphylaxis
National
NICE guideline [CG183]: Drug allergy: diagnosis and management
National
Drug Allergies - Thong B, Vervloet D, Torres Jaen, MJ (Updated 2021)
Local
Drug allergy: A 2022 practice parameter update
Local
Important questions in drug allergy and hypersensitivity: consensus papers from the 2018 AAAAI/WAO international drug allergy symposium
Local
Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: 2020 Update from the AAAAI
Local

Recent iatroX Q&As

  • What are the key steps in assessing a patient with a suspected drug allergy in primary care?Updated: 8/22/2025
  • How can I differentiate between a true drug allergy and an adverse drug reaction in my patients?Updated: 8/22/2025
  • What management strategies should I consider for a patient experiencing an anaphylactic reaction to a medication?Updated: 8/22/2025
  • When should I refer a patient with a history of drug hypersensitivity to a specialist for further evaluation?Updated: 8/22/2025
  • What documentation and follow-up actions are recommended for patients with a confirmed drug allergy?Updated: 8/22/2025
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