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Depression (Adults)

Assessment and treatment of depressive disorders in adults.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MSt MRCGP (General Practitioner)
Last reviewed: 21 October 2025
Mental Health
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regional clinical guidance

Depression (Adults): guidance by region

Recommendations, thresholds and pathways can differ. Open the page written for the jurisdiction you need.

United StatesMajor depressive disorder assessment and treatmentMental health · reviewed 2026-08-20CanadaDepressionMental health · reviewed 2026-08-20AustraliaDepressionMental health · reviewed 2026-08-20

Clinical Guidelines

CKS: Depression
National
NICE Clinical Guideline [CG90]
National
NICE guideline [NG222]
National
NICE guideline [NG222]: Depression in adults: treatment and management
National
American Psychiatric Association Practice Guideline for the Treatment of Patients with Major Depressive Disorder, Third Edition
Local
Institute for Clinical Systems Improvement (ICSI) Healthcare Guideline: Depression, Adults in Primary Care
Local
NICE Clinical Guideline 90: Depression in adults: recognition and management
Local
Province of British Columbia: Depression, Adults, Major Depressive Disorder in Adults - Diagnosis and Management
Local
US Preventive Services Task Force (USPSTF) Final Recommendation Statement: Depression in Adults: Screening (2016)
Local
VA/DoD Clinical Practice Guideline for the Management of Major Depressive Disorder
Local