Answer
Zoledronic acid is not metabolised and is excreted unchanged via the kidneys; 39 ± 16% of the dose is recovered in urine within 24 hours, while the remainder principally binds to bone and is slowly released into circulation for renal elimination.
Sources for this answer
- Zoledronic acid 4 mg/5 ml concentrate for solution for infusionTillomed Laboratories Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 4Document updated
Sources checked