Answer
The product information states that a specific reversal agent is unavailable. Major bleeding requires urgent specialist management; vitamin K, protamine and dialysis are not expected to reverse edoxaban effectively.
Sources for this answer
- Lixiana Film-Coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.