Answer
The product information warns against use in people with a history of asthma or wheezing because beta-1 selectivity is not absolute and bronchospasm can occur.
Sources for this answer
- Co-tenidone 50/12.5mg Film-Coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.