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Medicines difelikefalin acetateQuestion & answer

difelikefalin acetate · Medicine question

Is it a conventional opioid painkiller?

iatroX medicinesPublished 19 August 2026Reviewed 19 August 2026

The answer

Answer

No. It selectively activates peripheral kappa-opioid receptors to reduce itch and is not licensed as an analgesic.

Sources for this answer

Kapruvia (Difelikalin)emc · SmPC Current selected SmPC · Version 3

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The full medicine guide

difelikefalin acetate

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More questions about difelikefalin acetate

What is difelikefalin acetate used for?Is it taken by mouth?Can it be given at home?Can it make me sleepy?Can I drive after treatment?Does it interact with opioid painkillers?

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