Answer
Unopened products are generally refrigerated and must not be frozen. In-use temperature limits and permitted storage periods differ by formulation, so follow the product leaflet and discard insulin that has frozen or looks abnormal.
Sources for this answer
- Trurapi 100 units/ml solution for injection in pre filled pen — Current selected SmPCemc · Summary of Product Characteristics
- NovoRapid PumpCart — Current selected SmPCemc · Summary of Product Characteristics