How should Ambirix suspension in a pre-filled syringe be re-suspended before use?

Re-suspend Ambirix before use by holding the syringe upright in a closed hand and vigorously tipping it upside down and back for at least 15 seconds; inspect and repeat for at least another 15 seconds if needed until uniformly hazy white, not clear, and do not administer if foreign particles or abnormal appearance are present.