Answer
Eltrombopag or gefitinib could increase the bioavailability of mitoxantrone hydrochloride by inhibiting the BCRP transporter, for which mitoxantrone has been demonstrated to be a substrate in vitro.
Sources for this answer
- Onkotrone Injection 2 mg/ml concentrate for solution for infusionBaxter Healthcare Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated
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