Answer
In adults with growth hormone deficiency, somatropin may increase cyclosporine clearance through effects on CYP3A4-metabolised compounds, resulting in lower plasma levels, although the clinical significance is unknown.
Sources for this answer
- Norditropin FlexPro 5mg/1.5mL, 10mg/1.5mL, 15mg/1.5mLNovo Nordisk Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 28Document updated
Sources checked