How long can a reduction in nocturnal leg cramps take to become apparent with the Strides Pharma UK Ltd quinine sulfate 300 mg tablet product?

In adults, including older people, a reduction in nocturnal leg cramp frequency with the Strides Pharma UK Ltd quinine sulfate 300 mg tablet product may take up to 4 weeks to become apparent; patients should be monitored closely for adverse effects initially, and treatment stopped if there is no benefit after 4 weeks.