Answer
Tofersen is metabolised through exonuclease (3′- and 5′)-mediated hydrolysis and is not a substrate, inhibitor or inducer of CYP450 enzymes.
Sources for this answer
- Qalsody 100mg solution for injectionBiogen Idec Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 1Document updated
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