Answer
Although its metabolic pathway has not been characterised, spesolimab, a humanised IgG1 monoclonal antibody, is expected to be degraded into small peptides and amino acids through catabolic pathways similar to those for endogenous IgG.
Sources for this answer
- Spevigo 450 mg concentrate for solution for infusionLeo Laboratories Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 9Document updated
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