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Medicines riluzoleQuestion & answer

riluzole · Medicine question

How is riluzole thought to work in amyotrophic lateral sclerosis (ALS)?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Riluzole is proposed to inhibit glutamate processes in ALS, although its mode of action is unclear.

Sources for this answer

Riluzole 50 mg film-coated tabletsRanbaxy (UK) Limited a Sun Pharmaceutical Company · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated 14 May 2026

Sources checked 8 November 2026

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More questions about riluzole

What is riluzole indicated for in patients with amyotrophic lateral sclerosis (ALS)?Does Teglutik (riluzole) oral suspension need to be diluted with liquid before administration?How do high-fat meals affect the absorption of oral riluzole?How much sorbitol does Teglutik (riluzole) oral suspension contain per millilitre?Is riluzole contraindicated during pregnancy or breastfeeding?What adverse reactions were most commonly reported in clinical trials of riluzole in patients with ALS?

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