Answer
Intravenously administered mannitol is eliminated largely unchanged by glomerular filtration, with 80% excreted in urine within 3 hours and an adult elimination half-life of approximately 1–2 hours, prolonged in renal failure but not expected to be clinically significant.
Sources for this answer
- Osmohale Inhalation Powder, Hard CapsulePharmaxis Europe Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 5Document updated
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