Answer
Denosumab is expected to be metabolised and eliminated through immunoglobulin clearance pathways, degrading into small peptides and individual amino acids, and is unlikely to be eliminated through hepatic metabolic mechanisms.
Sources for this answer
- Prolia 60 mg solution for injection in pre-filled syringeAmgen Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 38Document updated
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