Answer
After oral administration, dabigatran etexilate, an inactive prodrug, is rapidly absorbed and converted into active dabigatran by esterase-catalysed hydrolysis in the plasma and liver.
Sources for this answer
- Pradaxa 75 mg hard capsulesBoehringer Ingelheim Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 47Document updated
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