Answer
Ceftobiprole medocaril sodium, the prodrug in Zevtera, is rapidly converted to active ceftobiprole by non-specific plasma esterases, releasing diacetyl, an endogenous human compound.
Sources for this answer
- Zevtera 500 mg powder for concentrate for solution for infusionADVANZ Pharma · emc · SmPC §5.2 Pharmacokinetic properties · Version 9Document updated
Sources checked