Answer
Oral methotrexate should be taken at least 6 hours before or after Calquence (acalabrutinib maleate) to minimise their potential interaction in the gastrointestinal tract.
Sources for this answer
- Calquence 100 mg film-coated tabletsAstraZeneca UK Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 8Document updated
Sources checked