Answer
Vorasidenib inhibits mutant IDH1 and IDH2 enzymes, reducing abnormal production of 2-hydroxyglutarate (2-HG), promoting malignant-cell differentiation and reducing their proliferation.
Sources for this answer
- Voranigo 10 mg film-coated tabletServier Laboratories Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated
Sources checked