voclosporin · Medicine question

How does voclosporin suppress T-cell activity?

iatroX medicinesPublished 8 November 2026

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Voclosporin inhibits calcineurin in a dose-dependent manner up to a maximum dose of 1.0 mg/kg, thereby inhibiting lymphocyte proliferation, T-cell cytokine production and expression of T-cell activation surface antigens.

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Lupkynis 7.9 mg soft capsulesOtsuka Pharmaceuticals (UK) Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated 3 November 2026

Sources checked 8 November 2026

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