Answer
Vinorelbine inhibits tubulin polymerization and binds preferentially to mitotic microtubules, affecting axonal microtubules only at high concentrations, thereby blocking mitosis at G2-M and causing cell death in interphase or at the following mitosis.
Sources for this answer
- Navelbine 30mg soft capsulePierre Fabre Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 34Document updated
Sources checked