vericiguat · Medicine question

How does vericiguat act on soluble guanylate cyclase?

iatroX medicinesPublished 8 November 2026

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Vericiguat directly stimulates soluble guanylate cyclase independently of and synergistically with nitric oxide, increasing intracellular cyclic guanosine monophosphate (cGMP).

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Verquvo 2.5 mg film-coated tabletsBayer plc · emc · SmPC §5.1 Pharmacodynamic properties · Version 2Document updated 24 February 2026

Sources checked 8 November 2026

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