rufinamide · Medicine question

How does valproate affect rufinamide blood concentrations?

iatroX medicinesPublished 8 November 2026

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Starting valproate in patients taking rufinamide may significantly increase rufinamide blood concentrations, so a rufinamide dose reduction should be considered.

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Rufinamide Eisai 100mg TabletsEisai Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 22Document updated 19 June 2025

Sources checked 8 November 2026

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