Answer
Vadadustat inhibits hypoxia-inducible factor prolyl-hydroxylase, increasing cellular hypoxia-inducible factor levels and thereby stimulating endogenous erythropoietin production, iron mobilisation and red blood cell production, resulting in a gradual rise in haemoglobin.
Sources for this answer
- Vafseo 300 mg film-coated tabletsMedice UK LTD · emc · SmPC §5.1 Pharmacodynamic properties · Version 2Document updated
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