Answer
Tizanidine hydrochloride’s exact mechanism is not fully clarified, but its predominant effect appears to involve reducing release of the excitatory amino acids glutamate and aspartate from spinal interneurons, thereby reducing abnormally increased muscle tone.
Sources for this answer
- Tizagelan 2 mg and 4 mg tabletsG.L Pharma UK Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 1Document updated
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