Answer
The Fc component of Elocta (efmoroctocog alfa) binds to the neonatal Fc receptor, using a natural recycling pathway that returns proteins to circulation and delays lysosomal degradation, giving it a longer plasma half-life than endogenous factor VIII.
Sources for this answer
- ELOCTA 250 IU powder and solvent for solution for injectionSwedish Orphan Biovitrum Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 11Document updated
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