tetrabenazine · Medicine question

How does tetrabenazine reduce chorea?

iatroX medicinesPublished 8 November 2026

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Answer

Tetrabenazine reversibly binds to vesicular monoamine transporters, inhibiting monoamine re-uptake in central presynaptic nerve terminals and depleting dopamine, which reduces movement and chorea severity.

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Tetrabenazine 25 mg TabletsRanbaxy (UK) Limited a Sun Pharmaceutical Company · emc · SmPC §5.1 Pharmacodynamic properties · Version 6Document updated 16 July 2025

Sources checked 8 November 2026

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