Answer
Tenofovir disoproxil succinate is converted to tenofovir and then tenofovir diphosphate, which inhibits HIV-1 reverse transcriptase and hepatitis B virus polymerase by competing with the natural deoxyribonucleotide substrate and terminating DNA chains after incorporation into DNA.
Sources for this answer
- Tenofovir disoproxil Dr. Reddys 245 mg Film-Coated TabletsDr. Reddy's Laboratories (UK) Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 12Document updated
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