Answer
Sumatriptan succinate selectively activates 5-HT1D receptors, causing cranial blood vessel constriction, and animal studies suggest it inhibits trigeminal nerve activity; both actions may contribute to migraine relief in humans.
Sources for this answer
- Imigran Injection, SubjectGlaxoSmithKline UK · emc · SmPC §5.1 Pharmacodynamic properties · Version 27Document updated
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