Answer
Somatrogon binds to growth hormone receptors, activating signalling including STAT5b and increasing serum IGF-1, which partially mediates its clinical effect, promoting metabolic changes, linear growth and increased growth velocity in children with growth hormone deficiency.
Sources for this answer
- Ngenla 60 mg solution for injection in pre-filled penPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated
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