Answer
Sebelipase alfa, a recombinant human lysosomal acid lipase, enters lysosomes after binding to cell-surface receptors and catalyses the hydrolysis of cholesteryl esters and triglycerides into free cholesterol, glycerol and free fatty acids.
Sources for this answer
- KANUMA 2mg/ml concentrate solutionAlexion Pharma UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 9Document updated
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