ritonavir · Medicine question

How does ritonavir directly inhibit HIV replication?

iatroX medicinesPublished 8 November 2026

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Ritonavir inhibits HIV-1 and HIV-2 aspartyl proteases, preventing processing of the gag-pol polyprotein precursor and producing immature HIV particles unable to initiate new rounds of infection.

Sources for this answer

Norvir 100 mg film-coated tabletsAbbVie Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 38Document updated 10 December 2025

Sources checked 8 November 2026

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Are any special handling or disposal precautions required for Norvir (ritonavir) 100 mg film-coated tablets?From what age is ritonavir indicated as a pharmacokinetic enhancer in combination treatment for HIV-1?How much sodium does each Norvir (ritonavir) 100 mg film-coated tablet contain?How should Norvir (ritonavir) 100 mg film-coated tablets be stored?Is ritonavir contraindicated in patients with decompensated liver disease?What bleeding risk is highlighted for patients with haemophilia A or B taking ritonavir?

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